表观遗传学是研究非DNA序列改变所造成的基因遗传变异。其中两个主要调控的机制為DNA甲基化的循环控制和组蛋白翻译后修饰。染色质的标记配置是一关键因素，一旦確立，染色质状态和基因表达蓝图即被建立，也就决定细胞表型特征。许多人类疾病和异常发生的原因，被發現與表观遗传信号出現異常有關，因此随着对逆转录或调节染色质的识别标志有越来越多的了解，新的干预治疗也有机会进一步被确定。
- 每月都有新货色不容错过
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- 本月免费抗体清单
| Introduction | The field of epigenetics involves the study of heritable changes in gene expression that occur in the absence of DNA sequence alterations. Two of the primary mechanisms responsible for epigenetic regulation include the fluid control of DNA methylation status and the posttranslational modification of histones. The resultant chromatin mark configurations are key elements in the establishment of gene expression profiles and chromatin states that determine a cell's phenotypic identity. Aberrant epigenetic signaling contributes to the genesis of many human diseases and disorders. As more is learned about reversing or modulating chromatin mark signatures, new opportunities for therapeutic intervention will likely be identified. | |||
| CatNo | Product Name | Host & Clonality | Reactivity | Application |
| GTX101249 | CBP antibody [C3], C-term | Rb pAb | Hu, Ms, Mk | ICC/IF, IHC, IHC-P, IP, WB, ChIP assay |
| GTX112912 | E2F1 antibody [N2C2], Internal | Rb pAb | Hu, Ms | ICC/IF, WB |
| GTX628007 | EED antibody [GT671] | Ms mAb | Hu, Ms, Rat | WB |
| GTX110384 | EZH2 antibody | Rb pAb | Hu | ICC/IF, WB, ChIP assay |
| GTX102170 | FOXM1 antibody | Rb pAb | Hu | WB, ChIP assay |
| GTX114462 | Histone H1.0 antibody | Rb pAb | Hu, Ms, Rat | ICC/IF, IHC-P, WB |
| GTX129418 | Histone H2A antibody | Rb pAb | Hu, Ms, Rat | IHC-P, WB |
| GTX115955 | Histone H2B antibody | Rb pAb | Hu, Ms | ICC/IF, IHC-P, WB |
| GTX122148 | Histone H3 antibody | Rb pAb | Hu, Ms, Dm, Mk, Rice | ICC/IF, IHC-P, IP, WB, ChIP assay |
| GTX128944 | Histone H3K27ac (acetyl Lys27) antibody | Rb pAb | Hu, Ms, Rat | Dot, ICC/IF, IHC-P, IP, WB, ChIP assay |
| GTX121677 | Histone H3K9me3 (trimethyl Lys9) antibody | Rb pAb | Hu, Ms, Rat | ICC/IF, IHC-P, WB, ChIP assay |
| GTX129560 | Histone H4 antibody | Rb pAb | Hu, Ms, Rat | ICC/IF, IHC-P, WB |
| GTX128957 | Histone H4K8ac (acetyl Lys8) antibody | Rb pAb | Hu, Ms, Rat | Dot, ICC/IF, IHC-P, IP, WB, ChIP assay |
| GTX102226 | KAP1 antibody [N3C2], Internal | Rb pAb | Hu, Ms | ICC/IF, IHC-P, IP, WB, ChIP assay |
| GTX101508 | KLF4 antibody | Rb pAb | Hu, Ms | FACS, IP, WB |
| GTX103289 | KLF5 antibody | Rb pAb | Hu, Ms, Rat | ICC/IF, IHC-P, WB |
| GTX116234 | Macro H2A.2 antibody [N3C3] | Rb pAb | Hu, Ms | ICC/IF, IHC-P, WB |
| GTX103322 | NRF2 antibody [N2C2], Internal | Rb pAb | Hu, Rat | ICC/IF, IHC-P, IP, WB, ChIP assay |
| GTX129156 | SIN3A antibody | Rb pAb | Hu, Ms, Rat | ICC/IF, IHC-P, IP, WB, ChIP assay |
| GTX112232 | ZHX2 antibody [C1C3] | Rb pAb | Hu | ICC/IF, IHC-P, IP, WB, ChIP-seq |
GeneTex还提供部分新品试用，本月以下新品可以申请试用：
新品试用清单
| CatNo | Product Name | Host & Clonality | Reactivity | Application |
| GTX130708 | ARID1B antibody | Rb pAb | Hu | WB |
| GTX131669 | CD44 antibody | Rb pAb | Hu | WB |
| GTX129847 | c-Fos antibody | Rb pAb | Hu | WB |
| GTX130061 | DGCR8 antibody | Rb pAb | Hu | IP, WB |
| GTX130971 | DHX9 antibody | Rb pAb | Hu | WB |
| GTX130427 | E-Cadherin (phospho Ser838/840) antibody | Rb pAb | Hu, Rat | IP, WB |
| GTX130006 | EIF2 alpha (phospho Ser52) antibody | Rb pAb | Rat | WB |
| GTX131422 | EIF2C2 antibody | Rb pAb | Hu | WB |
| GTX130417 | ErbB2 (phospho Tyr1139) antibody | Rb pAb | Hu | WB |
| GTX632015 | HIF2 alpha antibody [GT125] | Ms mAb | Hu, Ms, Rat | ICC/IF, IP, WB |
| GTX131224 | HOPX antibody | Rb pAb | Hu | WB |
| GTX130422 | IRF3 (phospho Ser386) antibody | Rb pAb | Hu | WB |
| GTX131804 | KHSRP antibody | Rb pAb | Hu, Ms | IHC-P, WB |
| GTX129315 | KLF9 antibody | Rb pAb | Hu | WB |
| GTX130240 | LSM1 antibody | Rb pAb | Hu | WB |
| GTX130964 | LSM2 antibody | Rb pAb | Ms | WB |
| GTX130428 | p120 Catenin (phospho Ser268) antibody | Rb pAb | Hu | WB |
| GTX130448 | p120 Catenin antibody | Rb pAb | Hu | WB |
| GTX129903 | p14ARF antibody | Rb pAb | Hu | ICC/IF, IP, WB |
| GTX130034 | PDX1 antibody | Rb pAb | Hu, Ms, Rat | WB |
| GTX130426 | PKC zeta (phospho Thr560) antibody | Rb pAb | Hu | WB |
| GTX131889 | Rif1 antibody | Rb pAb | Hu | IHC-P, WB |
| GTX632044 | RNaseH2B antibody [GT479] | Ms mAb | Hu | WB |
| GTX130214 | RPL32 antibody | Rb pAb | Hu | ICC/IF, IHC-P, WB |
| GTX130430 | RPS6 (phospho Ser235/236) antibody | Rb pAb | Hu | WB |
| GTX129100 | RUNX1 antibody | Rb pAb | Hu | WB |
| GTX129912 | STAG1 antibody | Rb pAb | Hu | IP, WB |
| GTX129876 | STAG2 antibody | Rb pAb | Hu, Ms | IP, WB |
| GTX132113 | STAT5B antibody | Rb pAb | Hu | WB |
| GTX130319 | TCPTP antibody | Rb pAb | Hu, Ms | IHC-P, IP, WB |
活动细则:
1. 本活动仅适用中国，并不得与其他优惠并用
2. 活动日期自2015年1月1日至1月31日
3. 每人限索取2管，且不得为同一货号
4. GeneTex保有活动解释权
