品          牌：   GeneTex

抗   体    名：   mTOR 抗体

抗体英文名：   mTOR antibody [C3], C-term

应用范围   ：    ICC/IF, IHC-P, IP, WB, ChIP assay

宿          主：    Rabbit

适应物种   ：    Human, Mouse, Rat

克  隆  性  ：    否

规         格：    100 ul

mTOR(mammalian Target of Rapamycin)哺乳动物雷帕霉素标靶蛋白，扮演着调节细胞分化、能量代谢及血管増生的角色。癌细胞中mTOR调控异常，导致HIF蛋白过度表现，癌细胞就会快增长。目前科学家积极研究mTOR抑制剂阻断P13K/AkT/mTOR路径中mTOR讯息传递，使癌细胞生长及蛋白质合成就受抑制或死亡。

GeneTex mTOR抗体3大特点

1. 应用范围完整，包含珍贵的ChIP等级：

ICC/IF, IHC-P, IP, WB, ChIP assay

2. 适用物种齐全：

Human, Mouse, Rat

3. 国际期刊引用及四星独立验证

● GTX101557 ChIP Image

● Cross-linked ChIP was performed with 293T chromatin extract and 5 μg of either control rabbit IgG or anti-mTOR antibody. The precipitated DNA was detected by PCR with primer set targeting to 45S rDNA promoter

● GTX101557 WB Image

● mTOR antibody detects mTOR protein by western blot analysis. Various whole cell extracts (30 μg) were separated by 5% SDS-PAGE, and the membrane was blotted with mTOR antibody (GTX101557) diluted by 1:1000.

● GTX101557 IHC-P Image

● mTOR antibody [C3], C-term detects mTOR protein at mitochondria on mouse stomach by immunohistochemical analysis.

Sample: Paraffin-embedded mouse stomach.

mTOR antibody [C3], C-term (GTX101557) diluted at 1:500.