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Human Topoisomerase II Alpha

Storage:
- Temperature: Store at -20°C or below for long-term storage.
- Conditions: Keep the product in a tightly sealed container to prevent moisture uptake. Avoid repeated freeze-thaw cycles to maintain product integrity.
- Stability: Stable for up to 6 months when stored properly. For best results, aliquot upon first use.

Product Description:
Human Topoisomerase II Alpha is an essential enzyme involved in DNA replication, transcription, and chromosomal segregation. It facilitates the unwinding and rewinding of DNA strands by inducing transient double-strand breaks. This recombinant enzyme is expressed in a suitable host system ensuring high purity and activity, making it ideal for various molecular biology applications.

Key Features:
- High Purity: Our product is purified to remove contaminants that can interfere with experimental outcomes.
- Activity: Demonstrates reliable topoisomerase activity, ensuring efficient DNA manipulation.
- Recombinant: Produced using advanced recombinant technology for consistency and reliability.
- Quality Control: Each batch undergoes rigorous testing to ensure optimal performance and reproducibility.

What's Included:
- Human Topoisomerase II Alpha enzyme: Supplied in a buffered solution to maintain stability.
- User Manual: Comprehensive guide detailing usage, handling, and safety precautions.
- Certificate of Analysis: Documented evidence of enzyme purity and activity for quality assurance.

Applications:
- Genomic Studies: Facilitates the analysis of DNA topology and chromosomal dynamics.
- Drug Discovery: Used in assays to screen for topoisomerase inhibitors, important in cancer therapeutic research.
- Molecular Cloning: Assists in the relaxation of supercoiled DNA, enhancing cloning efficiency.
- Cell Cycle Research: Helps investigate the role of topoisomerases in cell cycle progression and genetic stability.

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