Mouse Proteoglycan 4 (PRG4) Protein

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Storage

- Temperature: Store at -20°C for short-term storage. For long-term storage, it is recommended to store at -80°C.
- Conditions: Keep the protein in a tightly sealed container to prevent moisture absorption and contamination.
- Stability: Avoid repeated freeze-thaw cycles as these can degrade the protein. Aliquot the protein if necessary to minimize freeze-thaw events.

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Product Description

Mouse Proteoglycan 4 (PRG4), also known as Lubricin, is a mucin-like glycoprotein primarily known for its role in joint lubrication and protection of cartilage surfaces. It is expressed in synovial fluid and is crucial for maintaining healthy joint function. This protein is involved in reducing friction between cartilage surfaces, thereby preventing wear and tear in joints.

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Key Features

- High Purity: The protein is purified to ensure high purity, making it suitable for various applications in research and development.
- Bioactivity: Retains bioactivity and functionality for reliable experimental results.
- Recombinant Protein: Produced using advanced recombinant technology for consistency and reproducibility.
- Species Specificity: Derived from mouse, ideal for studies involving murine models.

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What's Included

- PRG4 Protein: Lyophilized or liquid form, depending on the product variant.
- Certificate of Analysis: Provides detailed information on protein purity, concentration, and bioactivity.
- Instructions for Use: Guidelines for reconstitution and handling.

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Applications

- Joint Research: Study of joint lubrication mechanisms and development of treatments for joint disorders such as osteoarthritis.
- Biomaterial Development: Use in designing biomaterials that mimic natural joint lubricants.
- Cell Culture: Supplementation in cell culture systems to study cell behavior in joint-like environments.
- Protein Interaction Studies: Exploration of interactions between PRG4 and other synovial proteins or cartilage components.
- Therapeutic Development: Potential use in developing therapies aimed at enhancing joint lubrication and repair.

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For optimal use and results, please refer to the detailed product manual provided with your purchase. If you have any questions regarding storage or applications, our technical support team is available to assist you.