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Product Description
Recombinant Human CHRNa1 protein is a synthetically produced protein that corresponds to the CHRNa1 gene segment from Ser21 to Leu255. This protein is part of the nicotinic acetylcholine receptor subunit alpha-1, which plays a crucial role in signal transmission across neuromuscular junctions. It is commonly used in research focused on neuromuscular diseases, signal transduction, and pharmacological studies.


Key Features
- Origin: Recombinant Human CHRNa1 protein expressed in a suitable host system (e.g., E. coli, yeast, or mammalian cells).
- Sequence: Amino acids from Ser21 to Leu255, ensuring high specificity and relevance for targeted applications.
- Purity: Typically greater than 90% as determined by SDS-PAGE.
- Activity: Demonstrated functionality in receptor binding and signal transduction assays.
- Scale: Available in various quantities to suit different research needs.


Storage
- Temperature: Store at -80°C for long-term stability. Avoid repeated freeze-thaw cycles.
- Buffer: Supplied in a buffer solution containing stabilizers to maintain protein integrity.
- Shelf Life: Typically stable for up to 12 months when stored properly.


What's Included
- Recombinant CHRNa1 Protein: Provided in a specified quantity with concentration details.
- Buffer Solution: Appropriate storage buffer for maintaining protein activity.
- Data Sheet: Detailed product information including sequence, purity, and usage guidelines.
- Certificate of Analysis: Quality control documentation ensuring product specifications.


Applications
- Research: Ideal for studies on neuromuscular disorders, synaptic transmission, and receptor pharmacology.
- Drug Discovery: Useful in screening compounds that modulate nicotinic acetylcholine receptor activity.
- Biochemical Assays: Suitable for binding assays, receptor interaction studies, and functional assays.
- Structural Studies: Can be used for crystallography or other structural analysis techniques to elucidate receptor architecture.

This information provides a comprehensive overview of the Recombinant Human CHRNa1 protein, catering to the needs of researchers in various fields.