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产品描述
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Certainly! To create a comprehensive product information sheet for the SARS-CoV-2 (2019-nCoV) Spike S1+S2 ECD-His Recombinant Protein, we can expand upon each aspect as follows:
Storage
- Temperature: Store at -20°C or lower for long-term storage. Avoid repeated freeze-thaw cycles.
- Stability: Stable for up to 12 months at -20°C. If stored at 4°C, use within one week.
- Packaging: The product is supplied in a lyophilized form to ensure stability during transport and storage.
Product Description
- Overview: This recombinant protein consists of the extracellular domain (ECD) of the SARS-CoV-2 Spike S1+S2 protein, engineered with a His-tag for easy purification and detection.
- Source: Expressed in a mammalian expression system to ensure proper folding and post-translational modifications.
- Molecular Weight: Approximately 140 kDa.
- Purity: Greater than 95% purity as confirmed by SDS-PAGE and HPLC analysis.
Key Features
- High Purity: Ensures reliable results in assays and experiments.
- His-tagged: Facilitates purification and detection via anti-His antibodies or affinity chromatography.
- Biologically Active: Retains native conformation and activity, suitable for binding assays and vaccine development.
- Versatility: Applicable to a wide range of research applications, including immunology, virology, and vaccine research.
What's Included
- Recombinant Protein: Vial containing lyophilized SARS-CoV-2 Spike S1+S2 ECD-His protein.
- Certificate of Analysis: Provides detailed information on the product's specifications and quality.
- User Guide: Instructions for reconstitution, storage, and application protocols.
- Safety Data Sheet (SDS): Information on handling and potential hazards.
Applications
- Vaccine Development: Utilize in the design of novel vaccines targeting SARS-CoV-2.
- Antibody Production: Serve as an antigen for generating monoclonal or polyclonal antibodies.
- Diagnostic Assays: Employ in ELISA or other immunoassays to detect SARS-CoV-2 antibodies in samples.
- Binding Studies: Investigate interactions with ACE2 and other potential therapeutic targets.
- Drug Screening: Test potential inhibitors of the Spike protein-ACE2 interaction.
- Structural Studies: Analyze conformation and structural dynamics using techniques like X-ray crystallography or cryo-EM.
This expanded product information aims to provide potential users with a clear understanding of the storage conditions, features, and applications of the SARS-CoV-2 Spike S1+S2 ECD-His Recombinant Protein.
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