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Product Name: IdeS Protease

Storage:

- Temperature: Store at -20°C for long-term stability.
- Conditions: Keep the product in a tightly sealed container to avoid contamination. Protect from light and moisture.
- Shelf Life: Typically stable for up to 12 months when stored properly. Avoid repeated freeze-thaw cycles to maintain activity.

Product Description:

IdeS Protease is an enzyme derived from *Streptococcus pyogenes* that specifically cleaves Immunoglobulin G (IgG) molecules at a single site below the hinge region, producing F(ab')2 and Fc fragments. This protease is highly efficient in IgG fragmentation, making it ideal for applications where antibody modification is required.

Key Features:

- Specificity: Cleaves IgG specifically, without affecting other proteins.
- Efficiency: Rapidly fragments IgG under optimal conditions.
- Purity: High purity and activity, ensuring reliable performance in experimental protocols.
- Versatility: Compatible with various IgG subclasses across different species.

What's Included:

- IdeS Protease Enzyme: Provided in a specified concentration and volume.
- Buffer: A compatible buffer solution for enzyme activity optimization.
- User Manual: Detailed instructions for use and troubleshooting.
- Certificate of Analysis: Verification of enzyme activity and purity.

Applications:

- Antibody Fragmentation: Ideal for generating F(ab')2 and Fc fragments for research and therapeutic purposes.
- Immunological Studies: Facilitates studies on antibody structure and function by providing consistent fragment generation.
- Analytical Techniques: Suitable for mass spectrometry and other analytical methods requiring antibody fragmentation.
- Therapeutic Development: Useful in the development of antibody-based therapeutics where modification of IgG is necessary.

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