Certainly! Here's a comprehensive product information guide for the Recombinant Human TGF-beta RI Protein (aa 200-503, His & GST Tag):

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Recombinant Human TGF-beta RI Protein (aa 200-503, His & GST Tag)

Product Description:
This recombinant protein represents the human Transforming Growth Factor-beta Receptor I (TGF-beta RI), covering amino acids 200-503. It is engineered with both His and GST tags for improved purification and detection. TGF-beta RI is part of the serine/threonine kinase family and plays a critical role in the TGF-beta signaling pathway, which is involved in numerous cellular processes such as proliferation, differentiation, and apoptosis. This product is ideal for research applications focused on signal transduction, receptor-ligand interactions, and disease modeling.

Key Features:
- Source: Expressed in [specify host, e.g., E. coli, HEK293 cells].
- Tags: His tag and GST tag for easy purification and enhanced solubility.
- Purity: Greater than 90% as determined by SDS-PAGE.
- Activity: Biologically active, capable of binding TGF-beta.
- Formulation: Lyophilized powder or liquid form, depending on your preference.
- Quality Assurance: Each batch is tested for endotoxin levels and bioactivity.

Storage:
- Short-term Storage: Store at 2-8°C for up to 1 month.
- Long-term Storage: For extended storage, keep at -20°C or -80°C. Avoid repeated freeze-thaw cycles.
- Reconstitution: Reconstitute with sterile water or buffer of choice. Once reconstituted, use immediately or aliquot and store at -80°C.

What's Included:
- Recombinant Human TGF-beta RI Protein (specified quantity and concentration).
- Certificate of Analysis detailing purity, endotoxin levels, and activity assays.
- User manual with detailed instructions for reconstitution and usage.

Applications:
- Signal Transduction Studies: Investigate the TGF-beta signaling pathway and its impact on cellular function.
- Drug Development: Screen potential inhibitors or activators of TGF-beta RI.
- Cancer Research: Explore the role of TGF-beta RI in tumor progression and metastasis.
- Protein-Protein Interactions: Study interactions with other signaling molecules.
- Biomarker Discovery: Evaluate potential biomarkers for diseases related to TGF-beta signaling.

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Ensure all handling and usage follow safety protocols and regulatory guidelines. For optimal results, please refer to the user manual provided with the product.