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产品描述
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Certainly! Here's a structured approach to supplement and improve the product information for the PAR/pADPr Antibody (10HA) [Unconjugated]:
Storage
- Recommended Storage Conditions: Store the antibody at -20°C for long-term storage. For short-term use, it can be stored at 4°C. Avoid repeated freeze-thaw cycles to preserve antibody integrity.
- Stability: When stored under proper conditions, the antibody remains stable for at least 12 months from the date of receipt.
- Shipping Conditions: The antibody is shipped on ice packs to maintain stability during transit.
Product Description
- Overview: The PAR/pADPr Antibody (10HA) is designed to specifically bind to poly(ADP-ribose) (PAR), a post-translational modification involved in various cellular processes including DNA repair and apoptosis.
- Clone: 10HA
- Host Species: Typically derived from mouse or rabbit.
- Isotype: IgG
- Purification: The antibody is purified via affinity chromatography to ensure high specificity and minimal cross-reactivity.
Key Features
- High Specificity: The antibody demonstrates strong specificity for poly(ADP-ribose), minimizing non-specific binding.
- Versatility: Suitable for various applications such as Western blot, immunoprecipitation, and immunofluorescence.
- Quality Assurance: Each batch undergoes rigorous quality control tests to ensure consistent performance.
- Unconjugated Format: Allows for flexibility in experimental design, enabling researchers to conjugate the antibody to a range of labels according to specific experimental needs.
What's Included
- Antibody Solution: Typically provided in a buffer solution containing stabilizers to maintain antibody activity.
- Product Data Sheet: Detailed documentation including recommended dilution ranges, example protocols, and troubleshooting tips.
- Certificate of Analysis: Verification of purity and performance metrics.
Applications
- Western Blot: Detect and quantify poly(ADP-ribose) modifications in cell or tissue lysates.
- Immunoprecipitation: Enrich PAR-modified proteins from complex samples for downstream analyses.
- Immunofluorescence: Visualize PAR localization and dynamics within cells using fluorescence microscopy.
- Research Areas: Ideal for studies in DNA damage response, cancer research, neurodegeneration, and cell death pathways.
With this improved product information, researchers can better understand the utility and application of the PAR/pADPr Antibody (10HA) [Unconjugated] in their experiments.
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