Certainly! Here's an improved and comprehensive product information guide for Recombinant Human Sphingosine Kinase 1 Protein (His & GST Tag):

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Product Information: Recombinant Human Sphingosine Kinase 1 Protein (His & GST Tag)

Storage:
- Temperature: Store at -80°C for long-term preservation.
- Stability: Avoid repeated freeze-thaw cycles to maintain protein integrity. If frequent use is anticipated, aliquot the protein into smaller volumes upon first thawing.
- Buffer: Ensure the protein is stored in a buffer that maintains its stability, typically containing a cryoprotectant like 50% glycerol.

Product Description:
- Source: Recombinant protein expressed in a suitable expression system, typically E. coli or yeast.
- Tag Information: Contains an N-terminal His tag and GST tag for enhanced solubility and simplified purification.
- Molecular Weight: Approximately 50 kDa, including tags.
- Purity: Greater than 90% as determined by SDS-PAGE.
- Function: Sphingosine Kinase 1 (SPHK1) catalyzes the phosphorylation of sphingosine to form sphingosine-1-phosphate (S1P), a lipid signaling molecule involved in cell growth, survival, and differentiation.

Key Features:
- High Purity and Activity: Ensures reliable results in downstream applications.
- Dual Tag System: Facilitates purification and enhances solubility.
- Versatile Use: Suitable for biochemical assays, structural studies, and functional analyses.
- Batch Consistency: Produced under strict quality control measures to ensure consistency across batches.

What's Included:
- Recombinant Protein: Provided in a specified volume and concentration.
- Certificate of Analysis: Includes detailed information on purity, activity, and expression details.
- Instruction Manual: Offers guidelines for storage, handling, and application.

Applications:
- Biochemical Assays: Utilized in enzyme activity assays to study sphingosine kinase activity.
- Drug Discovery: Screening potential inhibitors or activators of SPHK1 for therapeutic development.
- Signal Transduction Studies: Investigate the role of S1P in cellular signaling pathways.
- Structural Biology: Ideal for crystallography or NMR studies to elucidate the structure-function relationship.
- Cellular Studies: Examine the effects of SPHK1 on cell proliferation, apoptosis, and differentiation in various cell lines.

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This comprehensive product information guide is designed to support researchers in effectively utilizing Recombinant Human Sphingosine Kinase 1 Protein in their studies, providing them with essential details on storage conditions, product features, and potential applications.