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产品描述
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Certainly! Below is a structured format for supplementing and improving product information for the biological product "MUTAZYME, 10% S9 (PB/BNF Induced)":
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Product Name: MUTAZYME, 10% S9 (PB/BNF Induced)
Storage:
- Temperature: Store at -80°C for optimal stability.
- Handling: Minimize freeze-thaw cycles to maintain product integrity. Use aliquots if necessary.
- Shelf Life: When stored correctly, the product remains stable for up to 12 months from the date of manufacture.
Product Description:
MUTAZYME is a specialized biological reagent consisting of a 10% S9 liver fraction that has been induced with Phenobarbital (PB) and Beta-naphthoflavone (BNF). This product is used primarily in mutagenicity assays to simulate mammalian metabolism during in vitro testing. The S9 fraction is derived from the livers of rats treated with PB and BNF, which enhances the enzymatic activity necessary to mimic the metabolic processes that occur in humans.
Key Features:
- Enhanced Metabolic Activation: Induction with PB and BNF results in increased activity of cytochrome P450 enzymes, crucial for metabolic activation in mutagenicity assays.
- High Quality: Produced under stringent conditions to ensure consistency and reliability in experimental applications.
- Versatile Use: Suitable for use in various mutagenicity assays, including the Ames test and other genotoxicity studies.
- Validated Performance: Consistently performs in standard testing protocols, ensuring reproducibility and accuracy.
What's Included:
- MUTAZYME S9 Fraction: Provided in a ready-to-use format.
- Certificate of Analysis: Detailed documentation of product specifications, batch number, and expiration date.
- Usage Guidelines: Comprehensive instructions for optimal usage and storage.
Applications:
- Mutagenicity Testing: Ideal for use in the Ames test to assess the potential mutagenic effects of chemical compounds.
- Drug Development: Utilized during early-stage screening to evaluate the metabolic activation of pharmaceutical candidates.
- Environmental Testing: Applied in studies assessing the mutagenic potential of environmental pollutants and chemicals.
- Research: Supports investigations into xenobiotic metabolism and enzyme activity profiling.
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This format ensures that potential users have a clear understanding of the storage requirements, benefits, and applications of MUTAZYME, facilitating effective and informed use in their research and testing endeavors.
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