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产品描述
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Certainly! Here's a comprehensive overview of the Recombinant Human Ku70 & Ku80 Heterodimer Protein (His Tag) covering the aspects you mentioned:
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Product Name:
Recombinant Human Ku70 & Ku80 Heterodimer Protein (His Tag)
Storage:
- Temperature: Store at -80°C for long-term storage. For short-term use, store at -20°C.
- Conditions: Avoid repeated freeze-thaw cycles to maintain protein integrity.
- Stability: Once thawed, stable for up to 2 weeks at 4°C.
Product Description:
The Recombinant Human Ku70 & Ku80 Heterodimer Protein is expressed with a His Tag for easy purification and detection. Ku70 and Ku80 are components of the Ku heterodimer, crucial for DNA repair processes, particularly non-homologous end joining (NHEJ). The heterodimer binds to DNA double-strand break ends and recruits other proteins necessary for the repair process.
Key Features:
- High Purity: Over 95% purity as determined by SDS-PAGE.
- Recombinant Expression: Produced in a controlled environment ensuring high consistency and activity.
- His Tag: Facilitates easy purification and functional assays.
- Functionality: Retains DNA-binding activity essential for its role in DNA repair mechanisms.
What's Included:
- Recombinant Protein: Lyophilized or in solution form depending on your choice.
- Certificate of Analysis: Detailed document with purity, molecular weight, and functional activity data.
- User Manual: Instructions for reconstitution, storage, and handling.
Applications:
- DNA Repair Studies: Investigate the role of Ku heterodimer in NHEJ and other DNA repair pathways.
- Protein-Protein Interaction Assays: Study interactions between Ku heterodimer and other DNA repair proteins.
- Structural Biology: Analyze the structure-function relationship of Ku proteins.
- Drug Screening: Evaluate potential inhibitors targeting the Ku heterodimer for therapeutic interventions in diseases with defective DNA repair mechanisms.
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This format provides a detailed overview of the product and its specifications, ensuring that users have all necessary information for optimal usage.
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