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产品描述
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Certainly! Here's a detailed product information sheet for the biological product LPS-PG (LPS from P. gingivalis) - a TLR2/TLR4 agonist:
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Product Name:
LPS-PG (LPS from Porphyromonas gingivalis)
Storage:
- Temperature: Store at -20°C for long-term storage.
- Avoid: Repeated freeze-thaw cycles.
- Shelf Life: Stable for up to 12 months when properly stored.
- Handling: Thaw on ice before use to maintain integrity.
Product Description:
LPS-PG is a purified lipopolysaccharide derived from Porphyromonas gingivalis, a key bacterium implicated in periodontal disease. This product functions as an agonist for Toll-like receptors TLR2 and TLR4, making it an essential tool for studying inflammatory pathways and host-pathogen interactions in research related to oral health and systemic diseases.
Key Features:
- Purity: Highly purified for consistent results in experimental applications.
- Activity: Potent TLR2/TLR4 agonist, ideal for stimulating immune responses in vitro and in vivo.
- Relevance: Represents a critical component in periodontal disease research and understanding innate immune mechanisms.
- Versatility: Suitable for various applications, including cell culture, animal studies, and biochemical assays.
What's Included:
- LPS-PG Solution: Provided in a sterile, aqueous buffer for direct use in experiments.
- User Manual: Detailed instructions for handling, experimental setup, and troubleshooting.
- Safety Data Sheet (SDS): Comprehensive safety information for safe laboratory practices.
Applications:
- Immunological Studies: Investigate the activation of TLRs and subsequent signaling pathways in immune cells.
- Disease Research: Explore mechanisms of periodontal disease and potential therapeutic interventions.
- Drug Development: Screen potential inhibitors or modulators of TLR-mediated pathways.
- Cell Signaling: Study cytokine production, NF-kB activation, and other downstream effects following LPS stimulation.
- Pathogen Interaction: Examine host-pathogen interactions and the role of P. gingivalis in systemic conditions.
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This product is a crucial reagent for researchers focusing on immunology, microbiology, and oral health, providing insights into the molecular mechanisms of inflammation and infection. Always refer to the user manual and SDS for safe handling and optimal experimental results.
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