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Recombinant Human IRE1 Protein (aa 465-977), HPLC-Verified


Product Description
Recombinant Human IRE1 Protein encompasses amino acids 465 to 977, representing the functional core of the protein. IRE1 is a crucial sensor in the unfolded protein response (UPR) pathway, playing a significant role in maintaining cellular homeostasis and responding to endoplasmic reticulum stress. This recombinant protein is produced using advanced expression systems and purified to high standards, ensuring its activity and reliability for research applications.


Key Features
- High Purity: HPLC-verified for confirmed purity and activity.
- Biologically Active: Retains functional domains necessary for enzymatic activity.
- Recombinant Production: Produced in a controlled environment to ensure batch-to-batch consistency.
- Versatile Use: Suitable for various biochemical and cellular assays.


Storage
- Temperature: Store at -80°C for long-term stability.
- Avoid Repeated Freeze-Thaw Cycles: This can degrade the protein and affect its activity.
- Aliquoting Recommended: For convenient use and to minimize freeze-thaw cycles.


What's Included
- Recombinant Human IRE1 Protein (aa 465-977): Supplied in a buffer solution optimized for stability and activity.
- Storage Buffer: Typically includes stabilizers and preservatives to maintain protein integrity.
- Certificate of Analysis: Provides detailed information on purity, concentration, and activity.


Applications
- Protein-Protein Interaction Studies: Investigate interactions within the UPR pathway and other cellular processes.
- Enzymatic Activity Assays: Analyze kinase and RNase activities associated with IRE1 function.
- Cell Signaling Research: Study the role of IRE1 in stress response pathways.
- Drug Screening: Evaluate potential inhibitors or activators of IRE1 for therapeutic development.

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