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产品描述
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Certainly! Here's a detailed product information guide for the Recombinant Mouse TrkA Protein (hFc Tag):
Storage:
- Store the product at -20°C for short-term storage (up to 3 months).
- For long-term storage (up to 12 months), keep it at -80°C.
- Avoid repeated freeze-thaw cycles to maintain protein integrity.
- Once thawed, aliquot the protein into smaller volumes to prevent degradation.
- Use aseptic techniques to prevent contamination.
Product Description:
- The Recombinant Mouse TrkA Protein with an hFc Tag is produced in a mammalian expression system, ensuring proper folding and post-translational modifications.
- TrkA, a high-affinity receptor for nerve growth factor (NGF), plays a crucial role in the development and function of the nervous system.
- The hFc tag enhances protein stability and facilitates purification and detection processes.
- The protein is supplied in a buffered solution to maintain physiological pH and stability.
Key Features:
- High Purity: Greater than 95% purity as determined by SDS-PAGE.
- Biologically Active: Retains biological activity and can bind to NGF.
- Easy Detection: hFc tag allows for convenient detection and purification using anti-Fc antibodies or Protein A/G affinity chromatography.
- Versatile Use: Suitable for various applications, including cell signaling studies and receptor-ligand interaction assays.
What's Included:
- Recombinant Mouse TrkA Protein (hFc Tag) in a buffered solution.
- Certificate of Analysis with data on purity, concentration, and activity.
- Product manual with detailed instructions for use and handling.
Applications:
- Research: Investigate TrkA-mediated signal transduction pathways in neuronal cells.
- Drug Development: Study potential therapeutic targets for neurodegenerative diseases such as Alzheimer's and Parkinson's.
- Biochemical Assays: Utilize the protein in binding studies, enzyme-linked immunosorbent assays (ELISA), or Western blotting.
- Cell Culture: Assess the impact of TrkA activation on cell proliferation, differentiation, and survival in vitro.
- Structural Biology: Explore the protein's structure-function relationships using crystallography or NMR spectroscopy.
By optimizing these sections, you provide a comprehensive overview that can help researchers and developers utilize the Recombinant Mouse TrkA Protein effectively in their work.
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