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Storage

- Temperature: Store the kit at 2-8°C upon receipt.
- Shelf Life: The unopened kit is stable for up to 6 months from the date of manufacture when stored properly.
- After Opening: Once opened, components should be used within 2 months and stored according to the instructions provided for each reagent.
- Avoid Freezing: Do not freeze any of the kit components unless specified.


Product Description

The Human PKD1 / Polycystin Sandwich ELISA Kit is designed for the quantitative detection of PKD1 protein levels in human samples. Polycystin-1, encoded by the PKD1 gene, plays a critical role in the development and maintenance of renal structures, and its dysfunction is associated with autosomal dominant polycystic kidney disease (ADPKD). This kit offers high sensitivity and specificity for PKD1, facilitating research in renal disease mechanisms and potential therapeutic interventions.


Key Features

- High Sensitivity: Capable of detecting low concentrations of PKD1 for precise measurement.
- Specificity: Utilizes monoclonal antibodies for high specificity to PKD1, minimizing cross-reactivity.
- User-Friendly Protocol: Simplified procedure suitable for researchers at all levels of expertise.
- Reproducible Results: Consistent performance across multiple assays ensures reliability.
- Wide Range of Detection: Suitable for measuring PKD1 levels in a variety of human sample types.


What's Included

- Pre-coated 96-well Plate: Ready-to-use and specifically designed for PKD1 detection.
- Standard: Lyophilized PKD1 standard for generating a standard curve.
- Detection Antibody: Biotin-labeled anti-PKD1 antibody for enhanced sensitivity.
- HRP-Conjugated Secondary Antibody: Provides signal amplification.
- Sample Diluent: Optimized for sample preparation.
- Wash Buffer: Concentrated wash solution to ensure clean wells.
- Substrate Solution: TMB substrate for color development.
- Stop Solution: To halt the enzymatic reaction, allowing for measurement.
- Instruction Manual: Detailed protocol for assay performance.


Applications

- Disease Research: Investigation of ADPKD pathogenesis and progression.
- Biomarker Discovery: Identification of PKD1 as a potential biomarker for renal disease.
- Drug Development: Evaluation of therapeutic candidates targeting PKD1-related pathways.
- Clinical Studies: Support for epidemiological studies exploring genetic predisposition to kidney diseases.
- Basic Science: Advancing understanding of PKD1's role in cellular and molecular renal biology.

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This enhanced product information provides a comprehensive overview that can assist researchers and laboratory technicians in making informed decisions about using the Human PKD1 / Polycystin Sandwich ELISA Kit in their work.