STA-035,Rabbit Anti-4-Hydroxynonenal (HNE) Polyclonal Antibody,Cell Biolabs

Certainly! Here's a comprehensive product information guide for the Rabbit Anti-4-Hydroxynonenal (HNE) Polyclonal Antibody:


Storage
- Temperature: Store at -20°C for long-term storage. For short-term use, it can be stored at 4°C.
- Conditions: Keep the antibody in a tightly sealed vial to prevent contamination. Avoid repeated freeze-thaw cycles, which can degrade the antibody and reduce its effectiveness.
- Stability: When stored correctly, the antibody remains stable for up to 12 months.


Product Description
Rabbit Anti-4-Hydroxynonenal (HNE) Polyclonal Antibody is designed for the detection of 4-Hydroxynonenal, a marker of lipid peroxidation and oxidative stress. HNE is a reactive aldehyde formed during the oxidation of polyunsaturated fatty acids, making it significant in studying cellular oxidative damage and related pathologies. This polyclonal antibody provides high sensitivity and specificity for HNE, suitable for various research applications.


Key Features
- High Specificity: Targets 4-Hydroxynonenal with minimal cross-reactivity.
- Versatility: Suitable for use in various assays including Western blotting, immunohistochemistry, and ELISA.
- Quality Assurance: Produced using high-purity rabbit immunoglobulin.
- Reliable Performance: Consistent results across multiple applications.


What's Included
- Rabbit Anti-4-Hydroxynonenal (HNE) Polyclonal Antibody in a specified volume (e.g., 100 µL).
- Certificate of Analysis: Document detailing the antibody's specifications, validation data, and batch information.
- Usage Instructions: Guidelines for optimal use in various experimental setups.
- Safety Data Sheet (SDS): Information on handling, storage, and safety precautions.


Applications
- Western Blotting: Detects HNE-modified proteins in cell or tissue lysates.
- Immunohistochemistry (IHC): Localizes HNE in tissue sections, useful for studying oxidative stress in pathological conditions.
- Enzyme-Linked Immunosorbent Assay (ELISA): Quantifies HNE levels in biological samples.
- Research on Oxidative Stress: Investigate mechanisms of diseases related to oxidative damage, such as neurodegenerative disorders, cardiovascular diseases, and cancer.
- Biomarker Studies: Use as a biomarker for monitoring oxidative stress in various biological processes.

This antibody provides a valuable tool for researchers delving into the complex roles of lipid peroxidation and oxidative stress in health and disease.