STA-003,Goat Anti-Nitrotyrosine Polyclonal Antibody,Cell Biolabs

Certainly! Here's a detailed supplement and improvement for the product information of the Goat Anti-Nitrotyrosine Polyclonal Antibody:

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Storage:
- Store the antibody at -20°C for long-term preservation.
- Upon thawing, aliquot into smaller volumes to avoid repeated freeze-thaw cycles, which may affect antibody stability and performance.
- For short-term use, it can be stored at 2-8°C for up to one month.
- Protect from light to prevent degradation.

Product Description:
- This Goat Anti-Nitrotyrosine Polyclonal Antibody is designed for the detection of proteins that have undergone nitration, a post-translational modification often associated with oxidative stress.
- Nitrotyrosine is a marker for nitrosative damage, and its detection is crucial in the study of various pathological conditions, including inflammation and neurodegenerative diseases.
- The antibody is purified from goat serum and offers high specificity and affinity for nitrotyrosine residues.

Key Features:
- High Specificity: Recognizes nitrotyrosine residues with minimal cross-reactivity to other tyrosine modifications.
- Versatile Applications: Suitable for use in various assay formats, including Western blotting, immunohistochemistry, and ELISA.
- Robust Performance: Works effectively across a wide range of sample types, including cell lysates, tissue extracts, and serum.
- Quality Assurance: Each batch undergoes rigorous testing to ensure consistent performance and reliability.

What's Included:
- Antibody Solution: Provided in a buffer containing phosphate-buffered saline (PBS) with stabilizers and preservatives to ensure stability.
- Data Sheet: Detailed instructions for use, including recommended dilutions and protocols for different applications.
- Certificate of Analysis: Documentation of quality control testing and specifications for the specific batch.

Applications:
- Western Blotting: Detects nitrotyrosine-modified proteins in complex protein mixtures with high sensitivity.
- Immunohistochemistry: Suitable for staining tissue sections to localize nitrotyrosine modifications in situ.
- ELISA: Enables quantification of nitrotyrosine levels in various sample types, useful for assessing oxidative stress.
- Research on Oxidative Stress: Aids in the study of diseases where nitrosative stress plays a role, such as cardiovascular diseases, cancer, and neurodegeneration.
- Pathophysiological Studies: Utilized in understanding the mechanisms of nitration in disease progression and response.

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This improved product information aims to provide comprehensive details to assist researchers in effectively utilizing the Goat Anti-Nitrotyrosine Polyclonal Antibody in their studies.