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产品描述
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Certainly! Here's a comprehensive guide to supplement and improve the product information for the SKOV-3/Luc Cell Line:
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SKOV-3/Luc Cell Line Product Information
Storage
- Temperature: Store at -80°C for long-term storage. For immediate use, maintain cells in liquid nitrogen vapor phase.
- Conditions: Ensure that cells are stored in a sterile environment to prevent contamination.
- Handling: Thaw cells quickly in a 37°C water bath and transfer immediately to a pre-warmed growth medium.
Product Description
- Overview: The SKOV-3/Luc Cell Line is a human ovarian cancer cell line that has been genetically modified to express luciferase, allowing for easy monitoring of tumor growth and metastasis in vivo through bioluminescence imaging.
- Origin: Derived from the SKOV-3 ovarian adenocarcinoma cell line.
- Characteristics: These cells are adherent and exhibit epithelial-like morphology. They are known for their aggressive growth and are resistant to several chemotherapy drugs.
- Luciferase Expression: The luciferase gene allows researchers to track live cells in animal models through non-invasive imaging techniques.
Key Features
- Bioluminescent Imaging: Enables real-time monitoring of tumor progression and response to treatment.
- Chemotherapy Resistance: Useful for studying drug resistance mechanisms and testing new therapeutics.
- High Transfection Efficiency: Suitable for genetic manipulation and various molecular biology applications.
- Consistent Growth: Provides reliable data due to stable growth characteristics.
What's Included
- Cell Vial: Contains approximately 1 million cells per vial.
- Certificate of Analysis: Confirms cell line identity, viability, and absence of contamination.
- User Guide: Provides detailed instructions for thawing, culturing, and maintaining the cell line.
Applications
- Cancer Research: Study ovarian cancer pathogenesis, drug resistance, and treatment efficacy.
- In Vivo Imaging: Utilize the luciferase expression for bioluminescent imaging in animal models to track tumor growth and metastasis.
- Drug Screening: Evaluate the effectiveness of anti-cancer drugs and therapies on ovarian cancer cells.
- Gene Expression Studies: Investigate gene function and regulation in cancer progression and treatment response.
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This enhanced product information should provide researchers with the necessary details to effectively utilize the SKOV-3/Luc Cell Line in their studies.
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