ADV-157,Rho A L63 (Constitutively Active) Recombinant Adenovirus,Cell Biolabs

Certainly! Here's a comprehensive overview of the Rho A L63 (Constitutively Active) Recombinant Adenovirus product information, covering storage, product description, key features, what's included, and applications:

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Product Name: Rho A L63 (Constitutively Active) Recombinant Adenovirus

Storage:
- Temperature: Store at -80°C to ensure stability and longevity.
- Avoid: Repeated freeze-thaw cycles, which can diminish viral activity.
- Shelf Life: Typically stable for up to 6 months under recommended storage conditions.

Product Description:
Rho A L63 Recombinant Adenovirus is engineered to express a constitutively active form of Rho A, a small GTPase involved in various cellular processes including cytoskeletal dynamics, cell migration, and proliferation. This adenovirus vector delivers the Rho A L63 mutation directly into cells, enabling the study of Rho A-driven pathways and biological functions in a controlled environment.

Key Features:
- High Efficiency: Ensures effective delivery and expression of the Rho A L63 gene in target cells.
- Constitutively Active: The L63 mutation leads to persistent activation of Rho A, bypassing normal regulatory mechanisms.
- Versatile Application: Suitable for a range of cell types, including primary cells and cell lines.
- Quality Controlled: Manufactured under stringent quality standards to ensure consistency and reliability.

What's Included:
- Recombinant Adenovirus Stock: Provided in a specified volume and concentration (e.g., 1 x 10^10 viral particles/mL).
- Detailed Protocol: Instructions for transduction, handling, and experimental setup.
- Safety Data Sheet (SDS): Information on safe handling and disposal.
- Technical Support: Access to expert guidance for troubleshooting and optimization.

Applications:
- Cell Signaling Studies: Investigate the role of Rho A in cellular signaling pathways.
- Cytoskeletal Research: Explore its impact on actin dynamics and cell morphology.
- Cancer Research: Study Rho A-mediated effects on tumor cell motility and invasion.
- Drug Screening: Evaluate potential inhibitors targeting Rho A activity.
- Gene Function Analysis: Gain insights into the biological functions and mechanisms regulated by Rho A.

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This product information ensures that researchers have all necessary details to effectively utilize Rho A L63 Recombinant Adenovirus in their experiments, facilitating advancements in understanding cellular mechanisms and disease pathology.