ADV-150,Rac1 N17 (Dominant Negative) Recombinant Adenovirus,Cell Biolabs

Certainly! When enhancing the product information for Rac1 N17 (Dominant Negative) Recombinant Adenovirus, it's important to provide comprehensive details that will help users understand its use and handling. Below is an improved version of the product information covering Storage, Product Description, Key Features, What's Included, and Applications:

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Product Name: Rac1 N17 (Dominant Negative) Recombinant Adenovirus

Storage:
- Store at -80°C immediately upon receipt.
- Avoid repeated freeze-thaw cycles to preserve viral integrity and activity.
- If needed, aliquot the virus solution to minimize freeze-thaw cycles.

Product Description:
Rac1 N17 is a dominant negative mutant of Rac1, a small GTPase involved in regulating the actin cytoskeleton, cell migration, and various cellular processes. The N17 mutation in Rac1 is designed to inhibit normal Rac1 function by blocking its ability to bind GTP, thereby preventing downstream signaling. This recombinant adenovirus allows for efficient delivery of Rac1 N17 into target cells, facilitating studies on Rac1's role in cellular dynamics and signaling pathways.

Key Features:
- High Efficiency: Provides robust expression of Rac1 N17 in a wide range of cell types.
- Specificity: Dominant negative form specifically inhibits endogenous Rac1 activity.
- Versatility: Suitable for use in various models, including in vitro and in vivo systems.
- Quality Control: Produced under strict quality standards ensuring reproducibility and reliability.
- Safety: Replication-deficient adenovirus minimizes potential cytotoxicity.

What's Included:
- Rac1 N17 Recombinant Adenovirus (typically provided in a specified volume and concentration).
- Certificate of Analysis (detailing viral titer and purity).
- User Manual with guidelines on handling, transduction protocols, and troubleshooting.

Applications:
- Cell Signaling Studies: Explore Rac1's role in signal transduction pathways and its impact on cellular functions.
- Cell Migration and Invasion Assays: Investigate the effects of Rac1 inhibition on cell motility and invasion, critical for cancer and developmental research.
- Actin Cytoskeleton Analysis: Study the alterations in cytoskeletal organization upon Rac1 activity suppression.
- Pathway Analysis: Examine downstream effects of Rac1 inhibition on various biochemical pathways.
- In Vivo Studies: Utilize in animal models to understand Rac1's role in physiological and pathological processes.

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By providing detailed information on storage, product features, and applications, users can gain a better understanding of how to effectively use Rac1 N17 Recombinant Adenovirus in their research.