ADV-005,Cre Recombinant Adenovirus,Cell Biolabs

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Cre Recombinant Adenovirus

Storage:
- The Cre Recombinant Adenovirus should be stored at -80°C for long-term storage.
- Avoid repeated freeze-thaw cycles to maintain viral titer and effectiveness.
- Once thawed, it can be stored at 4°C for short-term use, typically up to one week.
- Ensure the storage area is free from contamination and the virus is kept in a tightly sealed container.

Product Description:
- The Cre Recombinant Adenovirus is engineered to express Cre recombinase, an enzyme that facilitates site-specific recombination of DNA between loxP sites.
- It is widely used in research for conditional gene knockout and gene activation in various cell types.
- The adenovirus vector allows efficient delivery and high-level expression of Cre recombinase in both dividing and non-dividing cells.

Key Features:
- High Efficiency: Facilitates efficient recombination in a variety of cell types, including primary cells and non-dividing cells.
- Broad Tropism: Capable of infecting a wide range of mammalian cells.
- Controlled Expression: Allows temporal control of gene expression and deletion.
- High Titer: Available in high concentrations to ensure effective transduction.
- Safety: Replication-deficient adenovirus minimizes risk of spreading in the host organism.

What's Included:
- Vial of Cre Recombinant Adenovirus: Supplied in a concentrated form.
- Certificate of Analysis: Detailed report confirming the quality and concentration of the virus.
- User Manual: Instructions for handling, storage, and application of the virus.
- Safety Data Sheet (SDS): Information on safe handling and potential hazards associated with the product.

Applications:
- Gene Knockout Studies: Used for creating tissue-specific knockout models by inducing recombination at loxP-flanked gene sequences.
- Gene Activation: Facilitates activation of genes that are controlled by floxed STOP sequences.
- Developmental Biology: Used to study gene function during development by temporally controlling gene expression.
- Cancer Research: Allows modification of oncogenes or tumor suppressor genes in cell lines and animal models.
- Neuroscience: Enables manipulation of neural circuits in the brain by targeting specific neuronal populations.

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