AP3731a,APR05234G,Phospho-FOXP3(S418) Antibody,Leading biology,abgent

Certainly! Here's a detailed supplement and improvement for the product information of the Phospho-FOXP3(S418) Antibody:

Storage:
- Store the Phospho-FOXP3(S418) Antibody at -20°C for long-term preservation.
- Once opened, aliquot the antibody to avoid repeated freeze-thaw cycles, which can degrade its quality.
- For short-term use, storing at 4°C is acceptable, but ensure that the vial is tightly sealed to prevent contamination.
- Avoid exposure to light to preserve antibody efficacy, as it may be sensitive to light-induced degradation.

Product Description:
- The Phospho-FOXP3(S418) Antibody is a highly specific antibody designed to detect the phosphorylation state of FOXP3 at serine 418.
- FOXP3 is a crucial transcription factor involved in the regulation of regulatory T cells (Tregs), playing a vital role in immune system modulation and tolerance.
- This antibody allows for the investigation of phosphorylation-dependent modulation of FOXP3 activity, which is important in understanding Treg function and autoimmune disorders.

Key Features:
- Specificity: High specificity for phosphorylated FOXP3 at the S418 site, ensuring precise detection in various assays.
- Sensitivity: Capable of detecting low levels of phosphorylated FOXP3, making it suitable for both qualitative and quantitative analyses.
- Versatility: Suitable for various applications including Western blotting, immunoprecipitation, immunofluorescence, and flow cytometry.

What's Included:
- A vial containing the Phospho-FOXP3(S418) Antibody at a concentration optimized for typical laboratory applications.
- A datasheet with detailed protocols for antibody applications, storage instructions, and troubleshooting tips.

Applications:
- Western Blotting: Ideal for detecting and analyzing the phosphorylation state of FOXP3 in cell lysates or tissue extracts.
- Immunoprecipitation: Useful for isolating phosphorylated FOXP3 from complex protein mixtures, facilitating downstream analysis.
- Immunofluorescence: Allows visualization of phosphorylated FOXP3 localization within cells, aiding in cellular and molecular studies.
- Flow Cytometry: Enables the quantification and characterization of phosphorylated FOXP3 in cell populations, useful for immunological research and clinical studies.

This comprehensive product information should help users effectively utilize the Phospho-FOXP3(S418) Antibody in their research and experimental workflows.