Certainly! Here’s a comprehensive product information guide for a Cas9 protein with a Nuclear Localization Signal (NLS):

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Product Information: Cas9 Protein with NLS

Storage
- Temperature: Store at -20°C or -80°C for long-term storage.
- Avoid Freeze-Thaw Cycles: Minimize repeated freeze-thaw cycles to preserve protein integrity.
- Buffer Conditions: Typically provided in a buffer containing glycerol to enhance stability.
- Shelf Life: Up to 12 months if stored properly at recommended temperatures.

Product Description
Cas9 protein with NLS is a CRISPR-associated endonuclease derived from *Streptococcus pyogenes*. It is engineered with a Nuclear Localization Signal (NLS) to facilitate its transport into the nucleus of eukaryotic cells. This protein is pivotal for genome editing applications, enabling precise DNA cleavage when guided by a single-guide RNA (sgRNA).

Key Features
- High Efficiency: Robust and precise DNA cleavage activity when complexed with sgRNA.
- Nuclear Localization: NLS ensures efficient nuclear import, enhancing genome editing efficiency in eukaryotic cells.
- Versatile: Compatible with various cell types and organisms.
- Purity: High purity levels, ensuring minimal off-target effects and maximal activity.
- Ready-to-use: Supplied in a form that allows for immediate use in experiments.

What's Included
- Cas9 Protein with NLS: A specified quantity based on selected product size (e.g., 100 µg, 500 µg).
- Storage Buffer: The protein is suspended in a storage buffer that maintains its stability.
- User Manual: Detailed instructions for use, including protocols for complex formation with sgRNA and transfection into cells.
- Certificate of Analysis: Information on purity, concentration, and activity.

Applications
- Genome Editing: Facilitates targeted gene modifications, including knockouts, insertions, and replacements.
- Functional Genomics: Study gene function by observing phenotypic consequences of gene edits.
- Gene Therapy Research: Investigate potential therapeutic interventions by correcting genetic defects.
- Biotechnology Development: Enhance agricultural or microbial strains through precise genetic engineering.
- Basic Research: Tool for studying DNA repair, replication, and recombination processes.

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This product information is designed to provide users with a clear understanding of the Cas9 protein with NLS, ensuring effective and efficient application in their research and development efforts.