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产品描述
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Certainly! Here's an enhanced product information sheet for the Cas9 protein with NLS:
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Product Name: Cas9 Protein with Nuclear Localization Signal (NLS)
Storage:
- Store at -80°C for long-term storage.
- For short-term use, the protein can be kept at -20°C for up to one month.
- Avoid repeated freeze-thaw cycles to maintain protein integrity.
- Store the protein in aliquots to minimize degradation risk.
Product Description:
The Cas9 protein with Nuclear Localization Signal (NLS) is a highly purified recombinant protein derived from the CRISPR-associated endonuclease Cas9, with an attached nuclear localization signal to facilitate its transport into the nucleus. This protein is designed for use in CRISPR-Cas9 genome editing applications, enabling researchers to introduce targeted genetic modifications in a variety of cell types. The inclusion of NLS enhances the efficiency of delivery into the nucleus, ensuring that the Cas9 protein can effectively access and edit genomic DNA.
Key Features:
- High Purity: Produced through stringent purification processes to ensure high levels of purity and activity.
- Nuclear Localization Signal (NLS): Enhances nuclear import, improving the efficiency of genome editing.
- Active Form: Delivered in an active form ready for immediate use in experiments.
- Versatile: Suitable for use in various cell types, including mammalian, plant, and bacterial cells.
- Quality Control: Each batch undergoes rigorous quality control testing to ensure consistent performance.
What's Included:
- Cas9 Protein with NLS: Provided in a buffer solution optimized for stability and activity.
- User Manual: Comprehensive instructions for storage, handling, and application.
- Certificate of Analysis: Documentation of quality control testing results for the specific lot.
Applications:
- Genome Editing: Use in CRISPR-Cas9 mediated gene knockout, knock-in, or other genome editing techniques.
- Gene Regulation: Employ in CRISPR interference (CRISPRi) or activation (CRISPRa) studies to modulate gene expression.
- Functional Genomics: Facilitate studies aimed at understanding gene function and interactions.
- Biotechnology Research: Applicable in the development of genetically modified organisms for research or therapeutic purposes.
- Synthetic Biology: Integration into synthetic biology projects for the creation of novel genetic circuits and organisms.
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This product information is designed to provide comprehensive details to researchers and laboratory professionals, ensuring they have the necessary information to effectively utilize the Cas9 protein with NLS in their experiments.
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