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Product Information for PGP9.5 Antibody [K49007_1G1]


Storage
- Temperature: Store at -20°C for long-term storage. For short-term storage, keep at 4°C.
- Conditions: Avoid repeated freeze-thaw cycles to maintain antibody integrity.
- Stability: Stable for 12 months at -20°C from date of receipt.


Product Description
- Overview: The PGP9.5 Antibody [K49007_1G1] is a monoclonal antibody specifically designed to detect protein gene product 9.5 (PGP9.5), a ubiquitin carboxyl-terminal hydrolase isozyme, which plays a critical role in the ubiquitin-proteasome system.
- Structure: IgG1 subclass with high specificity to the PGP9.5 antigen.
- Source: Produced in mouse and purified using protein G affinity chromatography.


Key Features
- Specificity: High specificity to PGP9.5 with minimal cross-reactivity with other proteins.
- Sensitivity: Capable of detecting low levels of PGP9.5 in various sample types.
- Format: Available as a liquid solution or lyophilized powder for convenience.
- Quality: Validated for western blot, immunohistochemistry, and ELISA applications.
- Concentration: Available in 1 mg/mL concentration.


What's Included
- Antibody Vial: One vial containing 100 µg of PGP9.5 Antibody [K49007_1G1].
- Data Sheet: Detailed product information including recommended dilution ratios and protocol suggestions.
- Certificate of Analysis: Verification of antibody specificity and performance metrics.


Applications
- Western Blotting: Ideal for detecting PGP9.5 in tissue lysates and cell extracts.
- Immunohistochemistry (IHC): Suitable for use on paraffin-embedded tissue sections to study neurodegenerative diseases.
- Enzyme-Linked Immunosorbent Assay (ELISA): Useful for quantifying PGP9.5 levels in biological samples.
- Research Areas: Neurology, cancer research, and studies involving the ubiquitin-proteasome pathway.
- Cellular Localization Studies: Facilitates understanding of PGP9.5 distribution in neurons and other cell types.

These improvements aim to provide comprehensive information on handling, usage, and potential applications of the PGP9.5 Antibody [K49007_1G1], ensuring researchers can maximize its utility in their studies.